5/18/2020 · M. leprae is an obligate intracellular parasite that multiplies preferentially in tissues at cooler temperature. Habitat: M. leprae is found in large number in infected nasal secretions of patients with lepromatous leprosy. Virulence factors: The virulence factors exhibited by M. leprae includes:, The reason behind this is because the in M. leprae, the drug is Mycobacterium leprae is a bacterium that causes leprosy, also known as Hansens disease, which is a chronic infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
2/11/2016 · Mycobacterium leprae colonizes the Schwann cells of the peripheral nervous system and can also live and grow within macrophages as a way to evade the host immune system . The bacteria express many virulence factors that allow for invasion of the nerve cells and nutritional access . The symptoms of leprosy are associated with the degree of host immune system response to the infection,.
12/1/2015 · Virulence Factors. Leprosy is a difficult infection to study since it cannot be grown in the laboratory. With recent scientific advancements, more of its infection mechanisms have been brought to light, but many details remain unresolved. M. leprae begins by infecting Schwann cells found on the exterior of the nerve cells axons. The bacterium uses appendages called adhesins to attach itself to.
Mycobacterium leprae | Mechanisms of Pathogenicity, Virulence Factors and Pathogenicity of Mycobacterium …
Mycobacterium leprae — Leprosy – microbewiki, Mycobacterium leprae — Leprosy – microbewiki